Fresh blood from desired animal species.
Partitioning of test compound measured between red blood cells (RBC) and plasma.
Test Compound Concentration
Percent Organic Solvent in Incubation
adjusted by 2-fold dilution of blood with PBS buffer prior to incubation
Number of Repeats
RBC-to-Plasma ratio (K
Test Compound Requirement:
1-2 mg dry powder or 100-200 µL of 10 mM DMSO stock solution.