N-Acetylation Using Human Recombinant N-Acetyltransferases or Liver Cytosol
Mammalian liver cytosol or major human recombinant N-acetyltransferases.
Formation of N-acetylated metabolites of test compound measured upon incubation with liver cytosol or recombinant N-acetyltransferases.
Position of acetylation in the test compound can be elucidated upon request.
Test Compound Concentration
Percent Organic Solvent in Incubation
Number of Repeats
Formation of N-acetylated metabolites (% of parent) and determination of acetylation site (optional).
Test Compound Requirement:
1-2 mg dry powder or 100-200 µL of 10 mM DMSO stock solution.