Aqueous Solubility, Kinetic
Phosphate Buffer Saline pH 7.4 (PBS); other aqueous systems available upon request.
Kinetic aqueous solubility measured by incubating test compound in PBS for 1 h, followed by determination of dissolved concentration against a calibration curve.
Test Compound Concentration
Percent Organic Solvent in Incubation
7.4 or as requested
Verapamil and Tamoxifen
UV Absorbance or LC-MS (LC-MS/MS if necessary)
Number of Repeats
Solubility of test compound (µM).
Test Compound Requirement:
1-2 mg dry powder or 100-200 µL of 10 mM DMSO stock solution.