CYP Reaction Phenotyping (Liver Microsomes)
Human liver microsomes.
Human CYP isoforms responsible for metabolism of test compound determined by measuring metabolism suppression in the presence of CYP isoform-selective inhibitors.
Test Compound Concentration
CYP isoform-selective probe substrates
Number of Repeats
Percent of metabolism of test compound suppressed by CYP isoform-selective inhibitors.
Test Compound Requirement:
2-3 mg dry powder or 100-200 µL of 10 mM DMSO stock solution.